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New opportunities for an industrial partner to aid the development of micro injection moulding in the production of micro needles

Country of Origin: United Kingdom
Reference Number: TOUK20170303002
Publication Date: 11 July 2017

Summary

A UK University had developed a process using micro injection mouldings to produce micro-needles using a medial grade polymer.  This will allow the self administration of  insulin and vaccines through the skin to be painless compared to the painful hypodermic needle injections administered by healthcare professionals.The university seeks industrial partners for development of the technology through a joint venture leading to a licence agreement and or technical cooperation agreement.

Description

Micro-needles are minimally invasive drug delivery devices that have the potential to deliver biological molecules such as insulin and vaccines through the skin in a painless way by self administering compared to painful hypodermic injections administered by a healthcare professional.
The micro needle is designed to enter the outer layer of the skin allowing the drug to act locally or be absorbed by the capillary system.

There are a number of manufacturing solutions to producing microneedles such as wet and dry etching or the machining of metals such as silicon dioxide and titanium. However these methods are not cost effective, clinically effective or easily sterilised for mass production.

This UK university has developed a novel process using micro injection mouldings to produce microneedles using a medical grade polymer. This allows the production of microneedles patches at a low cost while preventing any unwanted effects caused by the possible breakage of the needle tips into the skin, so allowing the drugs to be absorbed through the skin in a more controlled delivery rate.

The university is seeking industrial partners for co-development of this technology. Implementing this jointly by sharing their know how in the product development. The Industrial partner could also have the technical expertise and are already active in the field of injection mouldings but may want to diversify into the development of micro products for the medical sector. This could be through a joint venture leading to a licence agreement and or technical cooperation agreement.

Advantages and Innovations

- Allows for  the production of microneedle patches at a low cost
- Microneedles made using micro injection ,moulding prevent unwanted effects caused by breakages of the needle tips
- This process allows for a more controlled delivery of the drug
- The potential opportunities directly from the development of these technologies include the theragnostic autonomous delivery devices for insulin delivery.
- The microneedle could automatically monitor blood glucose levels and intermittently inject the amounts of insulin at appropriate times .

Stage Of Development

Proposal under development

Requested partner

Industrial partners, producing  injection moulding, are sought for the development of Micro needles using a medical grade polymer. These partners will have the know how and expertise but want to move into the micro field of production

Industrial partners that have the technology in micro injection mouldings and would like to work with a research organisation to co-develop products for the healthcare sector.

These partnerships would ideally be through a a joint venture agreement, leading to a licence agreement and or technical cooperation agreement

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