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Development and manufacturing of electrospun advanced materials for medical devices, drug delivery systems, coating and filtration

Country of Origin: France
Reference Number: TOFR20170711002
Publication Date: 12 July 2017

Summary

A French company, 35 years old, provides R&D and manufacturing services in the biomedical field and microtechnologies. Electrospinning allows manufacturing of materials made of nano- or microfibers that can be used for regenerative medicine, tissue engineering, drug delivery systems combined medical devices, filtration, coating of metallic parts. Already involved in EU projects, it's looking for research and manufacturing partnerships where electrospun materials lead to new advanced materials.

Description

The company’s expertise focuses mainly on class I to III medical devices, like long-term implants, implanted drug delivery and active medical devices, advanced transluminal technologies and in vitro diagnostic devices. It stands as a efficient partner to design, develop, scale up and manufacture devices based on electrospun materials in clean rooms ISO 5 to 8.

The devices, developed and manufactured by the company, are in all medical fields. Furthermore, the company is interested by developing electrospun materials for other fields.

The company has been involved in the design, development, characterization, scale up, manufacturing and pre-clinical investigations of medical devices made with electrospun materials. For such purpose, the company uses an industrial electrospinning system which controls the temperature and humidity rate ensuring repeatability. Moreover, the system can be programmed for all day and night electrospinning. Hence, ambitious projects can be realized.

The company has the know-how to electrospin bioresorbable and non-bioresorbable polymers and is always interested in electrospinning new polymers.

Furthermore, the company electrospins filters, patches, straight tubes and tubes with complex shapes. Metallic materials can be coated by electrospinning. In addition electrospun materials can be assembled. Characterization of electrospun materials and devices (fiber diameter, thickness, mechanical properties, in vitro functionality evaluation, drug loading and release) can be done.

The company can manufacture electrospun materials for pre- and clinical studies. These materials can be packaged in cleanroom ISO 5 to 8 prior to sterilization.

The company is looking for new challenges and cooperation with industrial partners willing to test, design and put on the market new devices using its innovative know-how.
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Advantages and Innovations

•	Strong expertise, knowledge to design, scale up and manufacture medical devices and implants combined to an innovative technology and know-how leading to devices with new advanced and competitive properties.

• Successfully developed devices in a short time frame in the field of tissue engineering and implanted drug delivery systems.

• All the innovation chain can be covered from design to packaging of the electrospun devices.

Stage Of Development

Field tested/evaluated

Stage Of Development Comment

The company has already developed electrospun materials for preclinical evaluation. The company has investigated the electrospinning of different kind of materials.

Requested partner

Industrial partners are sought working mainly in the healthcare sector and willing to explore, test, design, and manufacture new devices based on the electrospinning technology. The company has a strong interest in developing electrospun materials in all the following fields : cardiology, neurology, ophtalmology, urology and orthopaedics. New challenges in tissue regeneration or drug delivery systems would also be welcome. Industrial partners in other fields can be considered.

The type of cooperation will be studied depending on the needs. Cooperation in the framework of Horizon 2020 could be also considered.

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